Embryo biopsy is a cutting-edge procedure performed during Preimplantation Genetic Diagnosis (PGD) or Preimplantation Genetic Testing (PGT) to collect genetic information from embryos before they are transferred into the uterus. This technique helps identify chromosomal abnormalities or hereditary diseases, allowing embryologists to select healthy embryos for implantation and improving the chances of a successful pregnancy.

The Process of Embryo Biopsy

Embryo Development

The procedure is performed on embryos created during an assisted reproduction cycle, such as Intracytoplasmic Sperm Injection (ICSI). The embryos are carefully monitored from fertilization until they reach specific developmental stages, either on day 3 or day 5.

Day 3 Biopsy

• By the third day of development, the embryo consists of 6-8 cells.
• A single cell (blastomere) is extracted for genetic analysis.
• To achieve this, a small opening is made in the zona pellucida (ZP)—the embryo’s outer layer—using a laser or chemical agents.
• The cell is gently removed while ensuring the embryo remains intact and continues developing.

Day 5 Biopsy (Blastocyst Biopsy)

• By day 5, the embryo reaches the blastocyst stage, where its cells have started specializing.
• 4-5 cells are extracted from the trophectoderm, the outer layer that will form the placenta.
• The inner cell mass, which will develop into the fetus, remains untouched, making this method safer and less invasive for future embryo development.

Genetic Analysis and Embryo Monitoring

• The extracted cells are sent to a specialized laboratory for genetic testing.
• Meanwhile, the embryo is carefully monitored in the lab to ensure it continues developing until it is ready for transfer.

Precision and Expertise at Sakalli IVF

Embryo biopsy is a delicate and highly specialized procedure requiring precision and expertise. At Sakalli IVF, our experienced embryologists utilize advanced technology and techniques to ensure:

• The safety of the embryo throughout the biopsy process.
• Accurate genetic results to aid in embryo selection.

This procedure is an integral part of PGD and PGT, providing critical insights into embryo health. By identifying genetically healthy embryos, we help couples:

• Make informed decisions about their fertility treatments.
• Reduce the risk of genetic disorders in their offspring.
• Increase the likelihood of a successful pregnancy.

Discover Advanced Fertility Solutions at Sakalli IVF

At Sakalli IVF, we are committed to offering cutting-edge fertility treatments tailored to your needs.

To learn more about embryo biopsy and how it can improve your fertility journey, contact us today and take the first step toward a healthier and brighter future for your family.