What is Donor Genetic Matching?

March 12, 2025
What is Donor Genetic Matching?

Donor genetic matching is a critical step in fertility treatments that ensures genetic compatibility between the donor and recipient. This process helps minimize the risk of passing on recessive genetic diseases by analyzing the genetic data of both the donor (egg or sperm) and the recipient. By ensuring they do not share pathogenic variants in the same genes, genetic matching enhances the chances of a successful assisted reproduction outcome and helps ensure the birth of a healthy child.


Why Is Genetic Diversity Important in Fertility Treatments?

Genetic diversity plays a crucial role in fertility treatments. When both parents carry the same recessive genetic mutation, their child has a 25% chance of inheriting the disorder.

At Sakalli IVF, we conduct comprehensive genetic testing on donors to prevent the transmission of these conditions, ensuring a safer and more effective fertility treatment process.


How Does Genetic Matching Work?

Genetic Screening of Donors

  • Donors undergo an extensive genetic evaluation to identify potential mutations.

Compatibility Check

  • The recipient’s genetic profile is compared to the donor’s to ensure they do not share mutations in the same genes.

Risk Reduction

  • If both parents are carriers of the same mutation, there is a 25% chance their child could inherit the disease.
  • Genetic matching eliminates this risk by selecting a compatible donor.

Benefits of Donor Genetic Matching

Higher IVF Success Rates – By reducing genetic risks, genetic matching maximizes the chances of a healthy child and improves IVF success rates.

Reduced Risk of Genetic Diseases – This process significantly minimizes the likelihood of passing on recessive genetic disorders to offspring.

Better Donor Selection – Genetic evaluations enable fertility clinics to select the most suitable donors, ensuring healthier outcomes for future generations.


Limitations of Genetic Testing

While genetic testing has made significant advances, it primarily focuses on known mutations and specific genes, meaning some genetic risks may still remain unidentified. Additionally, the cost of genetic testing may be a consideration for some couples.


Start Your Journey Today

Discover how donor genetic matching can enhance your fertility treatment and provide the best possible outcome for your future child.

📞 Contact Sakalli IVF today to learn more about our advanced genetic testing and personalized fertility care options.

Copyright © Sakalli IVF. All rights reserved